Protein Variants | Comment | Organism |
---|---|---|
additional information | the enzyme without domain II (LPHDELTA2) is normally transported along the secretory pathway, but does not dimerize nor is enzymatically active | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
membrane | - |
Homo sapiens | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P09848 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | the polypeptide stretch in domain II between L735-R868 harbors a unique N-glycosylation site that is responsible for lactase phlorizin-hydrolase retention in the endoplasmic reticulum via association with calnexin and facilitates proper folding of domains I and III before ER exit of lactase phlorizin-hydrolase. A similar N-glycosylation site in domain IV shows comparable effects on the trafficking of lactase phlorizin-hydrolase-derived molecules | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
intestinal epithelium | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
lactase phlorizin-hydrolase | - |
Homo sapiens |