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Literature summary for 3.2.1.108 extracted from
- Decreased sucrase and lactase activity in iron deficiency is accompanied by reduced gene expression and upregulation of the transcriptional repressor PDX-1 (2005), Am. J. Physiol. Gastronintest. Liver Physiol., 289, G1108-G1114.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 27 | - |
lactose | 100 mM maleate buffer pH 6.0, 37°C | Rattus norvegicus |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| lactose + H2O | Rattus norvegicus | in rats grown under iron deficiency lactase-phlorizin hydrolase activity was 56.8% lower compared to control rats | D-galactose + D-glucose | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| jejunum | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| lactose + H2O | - |
Rattus norvegicus | D-galactose + D-glucose | - |
? | |
| lactose + H2O | in rats grown under iron deficiency lactase-phlorizin hydrolase activity was 56.8% lower compared to control rats | Rattus norvegicus | D-galactose + D-glucose | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| lactase | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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