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Literature summary for 3.2.1.105 extracted from

  • Yerkes, N.; Wu, J.X.; McCoy, E.; Galan, M.C.; Chen, S.; OConnor, S.E.
    Substrate specificity and diastereoselectivity of strictosidine glucosidase, a key enzyme in monoterpene indole alkaloid biosynthesis (2007), Bioorg. Med. Chem. Lett., 18, 3095-3098.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.1.105

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Catharanthus roseus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.071
-
 6-methylstrictosidine pH 6.0, 37°C Catharanthus roseus
0.092
-
 7-methylstrictosidine pH 6.0, 37°C Catharanthus roseus
0.12
-
 7-fluorostrictosidine pH 6.0, 37°C Catharanthus roseus
0.14
-
 8-methylstrictosidine pH 6.0, 37°C Catharanthus roseus
0.15
-
 6-fluorostrictosidine pH 6.0, 37°C Catharanthus roseus
0.22
-
 strictosidine pH 6.0, 37°C Catharanthus roseus
0.22
-
 5-methylstrictosidine pH 6.0, 37°C Catharanthus roseus
0.37
-
 6-methoxystrictosidine pH 6.0, 37°C Catharanthus roseus
0.43
-
 7-methoxystrictosidine pH 6.0, 37°C Catharanthus roseus

Organism

Organism UniProt Comment Textmining
Catharanthus roseus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-methylstrictosidine + H2O
-
 Catharanthus roseus D-glucose + 5-methylstrictosidine aglycone
-
 ?
6-fluorostrictosidine + H2O
-
 Catharanthus roseus D-glucose + 6-fluorostrictosidine aglycone
-
 ?
6-methoxystrictosidine + H2O
-
 Catharanthus roseus D-glucose + 6-methoxystrictosidine aglycone
-
 ?
6-methylstrictosidine + H2O
-
 Catharanthus roseus D-glucose + 6-methylstrictosidine aglycone
-
 ?
7-fluorostrictosidine + H2O
-
 Catharanthus roseus D-glucose + 7-fluorostrictosidine aglycone
-
 ?
7-methoxystrictosidine + H2O
-
 Catharanthus roseus D-glucose + 7-methoxystrictosidine aglycone
-
 ?
7-methylstrictosidine + H2O
-
 Catharanthus roseus D-glucose + 7-methylstrictosidine aglycone
-
 ?
8-methylstrictosidine + H2O
-
 Catharanthus roseus D-glucose + 8-methylstrictosidine aglycone
-
 ?
strictosidine + H2O
-
 Catharanthus roseus D-glucose + strictosidine aglycone
-
 ?
vincoside + H2O
-
 Catharanthus roseus D-glucose + vincoside aglycone
-
 ?
vincoside pent-4-yn-1-yl ester + H2O
-
 Catharanthus roseus D-glucose + vincoside pent-4-yn-1-yl ester aglycone
-
 ?