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Literature summary for 3.2.1.1 extracted from
- alpha-Amylase: an ideal representative of thermostable enzymes (2010), Appl. Biochem. Biotechnol., 160, 2401-2414.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| N172R/H156Y/A181T | the mutations increase the thermostability of alpha-amylase by 5fold | Bacillus licheniformis |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | Bacillus subtilis alpha-amylase requires roughly 4times more calcium for full activity than other alpha-amylases of nonbacterial nature | Bacillus subtilis |  |
| additional information | does not require Ca2+ | Pyrococcus furiosus | |
| additional information | does not require Ca2+ | Pyrococcus woesei |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 58000 | - |
- |
Bacillus licheniformis |
| 58000 | - |
SDS-PAGE | Bacillus amyloliquefaciens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glycogen + H2O | Lactiplantibacillus plantarum | - |
? | - |
? | |
| glycogen + H2O | Bacillus subtilis | - |
? | - |
? | |
| glycogen + H2O | Geobacillus stearothermophilus | - |
? | - |
? | |
| glycogen + H2O | Pyrococcus furiosus | - |
? | - |
? | |
| glycogen + H2O | Bacillus licheniformis | - |
? | - |
? | |
| glycogen + H2O | Bacillus amyloliquefaciens | - |
? | - |
? | |
| glycogen + H2O | Rhodothermus marinus | - |
? | - |
? | |
| glycogen + H2O | Pyrococcus woesei | - |
? | - |
? | |
| glycogen + H2O | Thermotoga maritima | - |
? | - |
? | |
| glycogen + H2O | Lederbergia lentus | - |
? | - |
? | |
| glycogen + H2O | Thermoactinomyces vulgaris | - |
? | - |
? | |
| glycogen + H2O | Rhizopus sp. | - |
? | - |
? | |
| glycogen + H2O | Thermomyces lanuginosus | - |
? | - |
? | |
| glycogen + H2O | Thermococcus litoralis | - |
? | - |
? | |
| glycogen + H2O | Thermothelomyces heterothallicus | - |
? | - |
? | |
| glycogen + H2O | Chloroflexus aurantiacus | - |
? | - |
? | |
| glycogen + H2O | Thermus filiformis | - |
? | - |
? | |
| glycogen + H2O | Mycothermus thermophilus | - |
? | - |
? | |
| glycogen + H2O | Lipomyces kononenkoae | - |
? | - |
? | |
| glycogen + H2O | Alicyclobacillus acidocaldarius | - |
? | - |
? | |
| glycogen + H2O | Dictyoglomus thermophilum | - |
? | - |
? | |
| glycogen + H2O | Thermococcus hydrothermalis | - |
? | - |
? | |
| glycogen + H2O | Desulfurococcus mucosus | - |
? | - |
? | |
| glycogen + H2O | Anoxybacillus flavithermus | - |
? | - |
? | |
| glycogen + H2O | Thermococcus profundus | - |
? | - |
? | |
| glycogen + H2O | Pyrodictium abyssi | - |
? | - |
? | |
| glycogen + H2O | Thermococcus fumicolans | - |
? | - |
? | |
| glycogen + H2O | Staphylothermus marinus | - |
? | - |
? | |
| glycogen + H2O | Lactobacillus amylovorus | - |
? | - |
? | |
| glycogen + H2O | Halothermothrix orenii | - |
? | - |
? | |
| glycogen + H2O | Thermococcus aggregans | - |
? | - |
? | |
| glycogen + H2O | Thermococcus celer | - |
? | - |
? | |
| glycogen + H2O | Thermococcus guaymasensis | - |
? | - |
? | |
| starch + H2O | Lactiplantibacillus plantarum | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Bacillus subtilis | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Geobacillus stearothermophilus | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Pyrococcus furiosus | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Bacillus licheniformis | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Bacillus amyloliquefaciens | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Rhodothermus marinus | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Pyrococcus woesei | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Thermotoga maritima | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Lederbergia lentus | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Thermoactinomyces vulgaris | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Rhizopus sp. | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Thermomyces lanuginosus | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Thermococcus litoralis | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Thermothelomyces heterothallicus | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Chloroflexus aurantiacus | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Thermus filiformis | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Mycothermus thermophilus | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Lipomyces kononenkoae | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Alicyclobacillus acidocaldarius | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Dictyoglomus thermophilum | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Thermococcus hydrothermalis | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Desulfurococcus mucosus | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Anoxybacillus flavithermus | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Thermococcus profundus | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Pyrodictium abyssi | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Thermococcus fumicolans | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Staphylothermus marinus | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Lactobacillus amylovorus | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Halothermothrix orenii | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Thermococcus aggregans | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Thermococcus celer | - |
malto-oligosaccharides | - |
? | |
| starch + H2O | Thermococcus guaymasensis | - |
malto-oligosaccharides | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Alicyclobacillus acidocaldarius | - |
- |
- |
| Anoxybacillus flavithermus | - |
- |
- |
| Bacillus amyloliquefaciens | - |
- |
- |
| Bacillus licheniformis | - |
- |
- |
| Bacillus subtilis | - |
- |
- |
| Chloroflexus aurantiacus | - |
- |
- |
| Desulfurococcus mucosus | - |
- |
- |
| Dictyoglomus thermophilum | - |
- |
- |
| Geobacillus stearothermophilus | - |
- |
- |
| Halothermothrix orenii | - |
- |
- |
| Lactiplantibacillus plantarum | - |
- |
- |
| Lactobacillus amylovorus | - |
- |
- |
| Lederbergia lentus | - |
- |
- |
| Lipomyces kononenkoae | - |
- |
- |
| Mycothermus thermophilus | - |
- |
- |
| Pyrococcus furiosus | - |
- |
- |
| Pyrococcus woesei | - |
- |
- |
| Pyrodictium abyssi | - |
- |
- |
| Rhizopus sp. | - |
- |
- |
| Rhodothermus marinus | - |
- |
- |
| Staphylothermus marinus | - |
- |
- |
| Thermoactinomyces vulgaris | - |
- |
- |
| Thermococcus aggregans | - |
- |
- |
| Thermococcus celer | - |
- |
- |
| Thermococcus fumicolans | - |
- |
- |
| Thermococcus guaymasensis | - |
- |
- |
| Thermococcus hydrothermalis | - |
- |
- |
| Thermococcus litoralis | - |
- |
- |
| Thermococcus profundus | - |
- |
- |
| Thermomyces lanuginosus | - |
- |
- |
| Thermothelomyces heterothallicus | - |
- |
- |
| Thermotoga maritima | - |
- |
- |
| Thermus filiformis | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glycogen + H2O | - |
Lactiplantibacillus plantarum | ? | - |
? | |
| glycogen + H2O | - |
Bacillus subtilis | ? | - |
? | |
| glycogen + H2O | - |
Geobacillus stearothermophilus | ? | - |
? | |
| glycogen + H2O | - |
Pyrococcus furiosus | ? | - |
? | |
| glycogen + H2O | - |
Bacillus licheniformis | ? | - |
? | |
| glycogen + H2O | - |
Bacillus amyloliquefaciens | ? | - |
? | |
| glycogen + H2O | - |
Rhodothermus marinus | ? | - |
? | |
| glycogen + H2O | - |
Pyrococcus woesei | ? | - |
? | |
| glycogen + H2O | - |
Thermotoga maritima | ? | - |
? | |
| glycogen + H2O | - |
Lederbergia lentus | ? | - |
? | |
| glycogen + H2O | - |
Thermoactinomyces vulgaris | ? | - |
? | |
| glycogen + H2O | - |
Rhizopus sp. | ? | - |
? | |
| glycogen + H2O | - |
Thermomyces lanuginosus | ? | - |
? | |
| glycogen + H2O | - |
Thermococcus litoralis | ? | - |
? | |
| glycogen + H2O | - |
Thermothelomyces heterothallicus | ? | - |
? | |
| glycogen + H2O | - |
Chloroflexus aurantiacus | ? | - |
? | |
| glycogen + H2O | - |
Thermus filiformis | ? | - |
? | |
| glycogen + H2O | - |
Mycothermus thermophilus | ? | - |
? | |
| glycogen + H2O | - |
Lipomyces kononenkoae | ? | - |
? | |
| glycogen + H2O | - |
Alicyclobacillus acidocaldarius | ? | - |
? | |
| glycogen + H2O | - |
Dictyoglomus thermophilum | ? | - |
? | |
| glycogen + H2O | - |
Thermococcus hydrothermalis | ? | - |
? | |
| glycogen + H2O | - |
Desulfurococcus mucosus | ? | - |
? | |
| glycogen + H2O | - |
Anoxybacillus flavithermus | ? | - |
? | |
| glycogen + H2O | - |
Thermococcus profundus | ? | - |
? | |
| glycogen + H2O | - |
Pyrodictium abyssi | ? | - |
? | |
| glycogen + H2O | - |
Thermococcus fumicolans | ? | - |
? | |
| glycogen + H2O | - |
Staphylothermus marinus | ? | - |
? | |
| glycogen + H2O | - |
Lactobacillus amylovorus | ? | - |
? | |
| glycogen + H2O | - |
Halothermothrix orenii | ? | - |
? | |
| glycogen + H2O | - |
Thermococcus aggregans | ? | - |
? | |
| glycogen + H2O | - |
Thermococcus celer | ? | - |
? | |
| glycogen + H2O | - |
Thermococcus guaymasensis | ? | - |
? | |
| starch + H2O | - |
Lactiplantibacillus plantarum | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Bacillus subtilis | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Geobacillus stearothermophilus | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Pyrococcus furiosus | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Bacillus licheniformis | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Bacillus amyloliquefaciens | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Rhodothermus marinus | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Pyrococcus woesei | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Thermotoga maritima | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Lederbergia lentus | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Thermoactinomyces vulgaris | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Rhizopus sp. | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Thermomyces lanuginosus | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Thermococcus litoralis | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Thermothelomyces heterothallicus | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Chloroflexus aurantiacus | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Thermus filiformis | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Mycothermus thermophilus | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Lipomyces kononenkoae | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Alicyclobacillus acidocaldarius | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Dictyoglomus thermophilum | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Thermococcus hydrothermalis | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Desulfurococcus mucosus | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Anoxybacillus flavithermus | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Thermococcus profundus | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Pyrodictium abyssi | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Thermococcus fumicolans | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Staphylothermus marinus | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Lactobacillus amylovorus | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Halothermothrix orenii | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Thermococcus aggregans | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Thermococcus celer | malto-oligosaccharides | - |
? | |
| starch + H2O | - |
Thermococcus guaymasensis | malto-oligosaccharides | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 58000 | Bacillus licheniformis |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| alpha-1,4-glucan-4-glucanohydrolase | - |
Lactiplantibacillus plantarum |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Bacillus subtilis |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Geobacillus stearothermophilus |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Pyrococcus furiosus |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Bacillus licheniformis |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Bacillus amyloliquefaciens |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Rhodothermus marinus |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Pyrococcus woesei |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Thermotoga maritima |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Lederbergia lentus |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Thermoactinomyces vulgaris |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Rhizopus sp. |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Thermomyces lanuginosus |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Thermococcus litoralis |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Thermothelomyces heterothallicus |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Chloroflexus aurantiacus |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Thermus filiformis |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Mycothermus thermophilus |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Lipomyces kononenkoae |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Alicyclobacillus acidocaldarius |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Dictyoglomus thermophilum |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Thermococcus hydrothermalis |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Desulfurococcus mucosus |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Anoxybacillus flavithermus |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Thermococcus profundus |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Pyrodictium abyssi |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Thermococcus fumicolans |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Staphylothermus marinus |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Lactobacillus amylovorus |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Halothermothrix orenii |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Thermococcus aggregans |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Thermococcus celer |
| alpha-1,4-glucan-4-glucanohydrolase | - |
Thermococcus guaymasensis |
| Amy | - |
Alicyclobacillus acidocaldarius |
| Amy | - |
Anoxybacillus flavithermus |
| Amy B | - |
Halothermothrix orenii |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 60 | - |
- |
Thermomyces lanuginosus |
| 60 | - |
- |
Mycothermus thermophilus |
| 60 | - |
- |
Anoxybacillus flavithermus |
| 60 | - |
- |
Halothermothrix orenii |
| 60 | 65 | - |
Rhizopus sp. |
| 60 | 65 | - |
Lactobacillus amylovorus |
| 61 | - |
- |
Rhodothermus marinus |
| 62.5 | - |
- |
Thermoactinomyces vulgaris |
| 65 | - |
- |
Lactiplantibacillus plantarum |
| 65 | - |
- |
Staphylothermus marinus |
| 70 | - |
- |
Bacillus subtilis |
| 70 | - |
- |
Bacillus amyloliquefaciens |
| 70 | - |
- |
Lederbergia lentus |
| 70 | - |
- |
Lipomyces kononenkoae |
| 70 | 80 | - |
Geobacillus stearothermophilus |
| 71 | - |
- |
Chloroflexus aurantiacus |
| 75 | - |
- |
Alicyclobacillus acidocaldarius |
| 80 | - |
- |
Thermococcus profundus |
| 85 | - |
- |
Thermococcus hydrothermalis |
| 85 | 90 | - |
Thermotoga maritima |
| 88 | - |
- |
Thermococcus litoralis |
| 90 | - |
- |
Dictyoglomus thermophilum |
| 90 | - |
- |
Thermococcus celer |
| 95 | - |
- |
Thermus filiformis |
| 95 | - |
- |
Thermococcus fumicolans |
| 100 | - |
- |
Pyrococcus furiosus |
| 100 | - |
- |
Bacillus licheniformis |
| 100 | - |
- |
Pyrococcus woesei |
| 100 | - |
- |
Thermothelomyces heterothallicus |
| 100 | - |
- |
Desulfurococcus mucosus |
| 100 | - |
- |
Pyrodictium abyssi |
| 100 | - |
- |
Thermococcus aggregans |
| 100 | - |
- |
Thermococcus guaymasensis |
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