Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | an approach using recombinant enzyme encapsulated within sterically stabilized liposomes to enhance diisopropyl fluorophosphates degradation | Alteromonas sp. |
Application | Comment | Organism |
---|---|---|
degradation | enzyme catalyse the hydrolysis of toxic organophosphorus cholinesterase-inhibiting compounds, including pesticides and chemical nerve agents | Alteromonas sp. |
degradation | approach to the use of enzyme encapsulated within liposomes, to protect against and treat chemical poisoning | Alteromonas sp. |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.57 | - |
sarin | - |
Alteromonas sp. | |
2.48 | - |
soman | - |
Alteromonas sp. | |
2.99 | - |
diisopropyl fluorophosphate | - |
Alteromonas sp. | |
14.2 | - |
paraoxon | - |
Alteromonas sp. |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Alteromonas sp. | - |
liposomes encapsulating enzyme | - |
Storage Stability | Organism |
---|---|
37°C, liposomes encapsulating enzyme incubated in blood, stable over 2 days | Alteromonas sp. |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
diisopropyl fluorophosphate + H2O | - |
Alteromonas sp. | diisopropyl phosphate + fluoride | - |
? | |
paraoxon + H2O | - |
Alteromonas sp. | diethylphosphate + 4-nitrophenol | - |
? | |
sarin + H2O | - |
Alteromonas sp. | ? | - |
? | |
soman + H2O | - |
Alteromonas sp. | ? | - |
? |