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Literature summary for 3.1.8.2 extracted from

  • Cheng, T.C.; Harvey, S.P.; Chen, G.L.
    Cloning and expression of a gene encoding a bacterial enzyme for decontamination of organophosphorus nerve agents and nucleotide sequence of the enzyme (1996), Appl. Environ. Microbiol., 62, 1636-1641.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
degradation enzyme catalyse the hydrolysis of toxic organophosphorus cholinesterase-inhibiting compounds, including pesticides and chemical nerve agents Alteromonas sp.
degradation enzyme is capable of detoxifying chemical warfare agents by hydrolysis Alteromonas sp.

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Alteromonas sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Alteromonas sp. the natural substrates for enzyme are unknown, enzyme may, in nature, be used in peptide metabolism ?
-
?

Organism

Organism UniProt Comment Textmining
Alteromonas sp.
-
JD6.5, halophilic bacterium
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
300
-
-
Alteromonas sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
diisopropyl fluorophosphate + H2O
-
Alteromonas sp. diisopropyl phosphate + fluoride
-
?
additional information the natural substrates for enzyme are unknown, enzyme may, in nature, be used in peptide metabolism Alteromonas sp. ?
-
?