Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.8.1 extracted from

  • Bizon, A.; Milnerowicz, H.
    The effect of divalent metal chelators and cadmium on serum phosphotriesterase, lactonase and arylesterase activities of paraoxonase 1 (2018), Environ. Toxicol. Pharmacol., 58, 77-83 .
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
CdCl2 60.6% residual activity after 24 h in the presence of 0.02 mg/ml CdCl2 Homo sapiens
D-penicillamine 20.2% residual activity after 24 h in the presence of 0.2 mg/ml D-penicillamine Homo sapiens
EDTA 65.7% residual activity after 24 h in the presence of 0.05 mg/ml EDTA Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ the enzyme has two Ca2+ binding sites Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood serum
-
Homo sapiens
-

Storage Stability

Storage Stability Organism
4°C, the enzyme activity is significantly lower after 48 h as well as after 1, 2 and 4 weeks storage when compared to enzyme activities assayed in fresh serum Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
paraoxon ethylene + H2O
-
Homo sapiens 4-nitrophenol + diethyl phosphate
-
?