Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
NaCl | salt-stimulated activity | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
serum | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
paraoxon + H2O | - |
Homo sapiens | 4-nitrophenol + diethyl phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
paraoxonase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | basal and salt-stimulated paraoxonase activity is significantly lower in patients with gestational diabetes mellitus compared to controls, while lipid hydroperoxide levels are significantly higher. Among gestational diabetes patients, serum paraoxonase activity is inversely correlated with lipid hydroperoxide levels. Decreased serum paraoxonase activity may play a role in the potential early pathogenesis for atherosclerotic heart disease in gestational diabetes mellitus beyond its antioxidant properties | Homo sapiens |