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Literature summary for 3.1.8.1 extracted from

  • Kotani, K.; Kimura, S.; Tsuzaki, K.; Sakane, N.; Komada, I.; Schulze, J.; Gugliucci, A.
    Reduced paraoxonase 1/arylesterase activity and its post-therapeutic increase in obstructive sleep apnea syndrome: A preliminary study (2008), Clin. Chim. Acta, 395, 184-185.
    View publication on PubMed

Application

Application Comment Organism
medicine the enzyme carried by high-density lipoprotein, exerts a protective effect against oxidative damage of cells and lipoproteins, modulating the susceptibility of high-density lipoprotein to atherogenic modifications and has an anti-inflammatory role, low PON1 activity is a risk factor for cardiovascular disease Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme carried by high-density lipoprotein, exerts a protective effect against oxidative damage of cells and lipoproteins, modulating the susceptibility of high-density lipoprotein to atherogenic modifications and has an anti-inflammatory role, low PON1 activity is a risk factor for cardiovascular disease ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens P27169
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme carried by high-density lipoprotein, exerts a protective effect against oxidative damage of cells and lipoproteins, modulating the susceptibility of high-density lipoprotein to atherogenic modifications and has an anti-inflammatory role, low PON1 activity is a risk factor for cardiovascular disease Homo sapiens ?
-
?
paraoxon + H2O
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Homo sapiens diethylphosphate + 4-nitrophenol
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?

Synonyms

Synonyms Comment Organism
paraoxonase 1
-
Homo sapiens
PON-1
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Homo sapiens