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Literature summary for 3.1.8.1 extracted from

  • Blum, M.M.; Timperley, C.M.; Williams, G.R.; Thiermann, H.; Worek, F.
    Inhibitory potency against human acetylcholinesterase and enzymatic hydrolysis of fluorogenic nerve agent mimics by human paraoxonase 1 and squid diisopropyl fluorophosphatase (2008), Biochemistry, 47, 5216-5224.
    View publication on PubMed
Search for more literature for 3.1.8.1

Organism

Organism UniProt Comment Textmining
Homo sapiens P27169
-
-

Purification (Commentary)

Purification (Comment) Organism
Cibacron Blue 3GA agarose gel chromatography and Q-Sepharose resin chromatography Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-methylethyl 2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl methylphosphonate + H2O
-
 Homo sapiens ?
-
 ?
1-methylethyl 4-methyl-2-oxo-2H-chromen-7-yl methylphosphonate + H2O
-
 Homo sapiens ?
-
 ?
2-methylpropyl 2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl methylphosphonate + H2O
-
 Homo sapiens ?
-
 ?
2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl N,N,N',N'-tetramethyldiamidophosphate + H2O
-
 Homo sapiens ?
-
 ?
3-chloro-4-methyl-2-oxo-2H-chromen-7-yl 1-methylethyl methylphosphonate + H2O
-
 Homo sapiens ?
-
 ?
3-chloro-4-methyl-2-oxo-2H-chromen-7-yl 2-methylpropyl methylphosphonate + H2O
-
 Homo sapiens ?
-
 ?
3-chloro-4-methyl-2-oxo-2H-chromen-7-yl cyclohexyl methylphosphonate + H2O
-
 Homo sapiens ?
-
 ?
3-chloro-4-methyl-2-oxo-2H-chromen-7-yl diethyl phosphate + H2O
-
 Homo sapiens ?
-
 ?
3-chloro-4-methyl-2-oxo-2H-chromen-7-yl dimethyl phosphate + H2O
-
 Homo sapiens ?
-
 ?
3-chloro-4-methyl-2-oxo-2H-chromen-7-yl ethyl methylphosphonate + H2O
-
 Homo sapiens 3-chloro-7-hydroxy-4-methyl-2H-chromen-2-one + ethyl methylphosphonate
-
 ?
4-methyl-2-oxo-2H-chromen-7-yl 2-methylpropyl methylphosphonate + H2O
-
 Homo sapiens 2-methylpropyl methylphosphonate + 7-hydroxy-4-methyl-2H-1-benzopyran-2-one
-
 ?
4-methyl-2-oxo-2H-chromen-7-yl N,N,N',N'-tetramethyldiamidophosphate + H2O
-
 Homo sapiens N,N,N',N'-tetramethylphosphorodiamidic acid + 7-hydroxy-4-methyl-2H-1-benzopyran-2-one
-
 ?
bis(1-methylethyl) 2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl phosphate + H2O
-
 Homo sapiens dipropan-2-yl phosphate + 7-hydroxy-4-(trifluoromethyl)-2H-1-benzopyran-2-one
-
 ?
bis(1-methylethyl) 4-methyl-2-oxo-2H-chromen-7-yl phosphate + H2O
-
 Homo sapiens dipropan-2-yl phosphate + 7-hydroxy-4-methyl-2H-1-benzopyran-2-one
-
 ?
cyclohexyl 2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl methylphosphonate + H2O
-
 Homo sapiens cyclohexyl methylphosphonate + 7-hydroxy-4-(trifluoromethyl)-2H-1-benzopyran-2-one
-
 ?
cyclohexyl 4-methyl-2-oxo-2H-chromen-7-yl methylphosphonate + H2O
-
 Homo sapiens cyclohexyl methylphosphonate + 7-hydroxy-4-methyl-2H-1-benzopyran-2-one
-
 ?
cyclosarin + H2O
-
 Homo sapiens ?
-
 ?
diethyl 2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl phosphate + H2O
-
 Homo sapiens diethyl phosphate + 7-hydroxy-4-(trifluoromethyl)-2H-1-benzopyran-2-one
-
 ?
diisopropyl fluorophosphate + H2O
-
 Homo sapiens ?
-
 ?
dimethyl 2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl phosphate + H2O
-
 Homo sapiens dimethyl phosphate + 7-hydroxy-4-(trifluoromethyl)-2H-1-benzopyran-2-one
-
 ?
dimethyl 4-methyl-2-oxo-2H-chromen-7-yl phosphate + H2O
-
 Homo sapiens ?
-
 ?
ethyl 2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl methylphosphonate + H2O
-
 Homo sapiens ethyl methylphosphonate + 7-hydroxy-4-(trifluoromethyl)-2H-1-benzopyran-2-one
-
 ?
ethyl 4-methyl-2-oxo-2H-chromen-7-yl methylphosphonate + H2O
-
 Homo sapiens ethyl methylphosphonate + 7-hydroxy-4-methyl-2H-1-benzopyran-2-one
-
 ?
N-[2-[ethoxy(methyl)phosphoryl]sulfanethyl]-N-propan-2-ylpropan-2-amine + H2O the enzyme shows only minimal activity against the nerve agent VX Homo sapiens S-[2-(diisopropylamino)ethyl]-methylphosphonothioic acid + ethanol
-
 ?
O,O-dimethyl O-(4-methyl-2-oxo-2H-chromen-7-yl) thiophosphate + H2O
-
 Homo sapiens ?
-
 ?
O,O-dimethyl O-[2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl] thiophosphate + H2O
-
 Homo sapiens ?
-
 ?
paraoxon + H2O
-
 Homo sapiens diethylphosphate + 4-nitrophenol
-
 ?
sarin + H2O
-
 Homo sapiens ?
-
 ?
soman + H2O
-
 Homo sapiens ?
-
 ?
tabun + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
paraoxonase
-
 Homo sapiens
PON1
-
 Homo sapiens