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Literature summary for 3.1.6.8 extracted from
- Purification and properties of arylsulphatase A from chicken brain (1972), Biochem. J., 126, 1025-1033.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ascorbate | alone no effect, enhances the inhibition by Cu2+ | Gallus gallus |  |
| CN- | - |
Gallus gallus | |
| Cu2+ | inhibition enhanced in presence of carbonyl reagents or ascorbic acid | Gallus gallus | |
| F- | - |
Gallus gallus | |
| N-ethylmaleimide | no inhibition at pH 5.5, but at pH 5.0 | Gallus gallus | |
| p-hydroxymercuribenzoate | no inhibition at pH 5.5, but at pH 5.0 | Gallus gallus | |
| PO43- | - |
Gallus gallus | |
| SO32- | - |
Gallus gallus | |
| SO42- | - |
Gallus gallus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| lysosome | - |
Gallus gallus | 5764 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cerebroside 3-sulfate + H2O | Gallus gallus | - |
cerebroside + sulfate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Gallus gallus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Gallus gallus |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| a cerebroside 3-sulfate + H2O = a cerebroside + sulfate | hydrolyses galactose-3-sulfate residues in a number of lipids, also hydrolyses ascorbate 2-sulfate and many phenol sulfates, enzymes catalyze in addition to reaction of EC 3.1.6.8 also arylsulfatase reaction EC 3.1.6.1 | Gallus gallus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Gallus gallus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 1.5 | - |
nitrocatechol sulfate | Gallus gallus |
Storage Stability
| Storage Stability | Organism |
|---|---|
| 0°C, 2 months | Gallus gallus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cerebroside 3-sulfate + H2O | - |
Gallus gallus | cerebroside + sulfate | - |
? | |
| nitrocatechol sulfate + H2O | - |
Gallus gallus | nitrocatechol + sulfate | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay | Gallus gallus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5 | 5.5 | pH optimum depends on time of incubation, 5-20 min: pH 5.5, 30-90 min: pH 5.0 | Gallus gallus |
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