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Literature summary for 3.1.6.6 extracted from

  • Osteras, M.; Boncompagni, E.; Vincent, N.; Poggi, M.C.; Le Rudulier, D.
    Presence of a gene encoding choline sulfatase in Sinorhizobium meliloti bet operon: choline-O-sulfate is metabolized into glycine betaine (1998), Proc. Natl. Acad. Sci. USA, 95, 11394-11399.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.6.6

Activating Compound

Activating Compound Comment Organism Structure
choline formation of the enzyme is induced by Sinorhizobium meliloti
Choline sulfate formation of the enzyme is induced by Sinorhizobium meliloti

Inhibitors

Inhibitors Comment Organism Structure
NaCl slight inhibition at high concentrations Sinorhizobium meliloti
phosphorylcholine competitive inhibition Sinorhizobium meliloti

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
choline sulfate + H2O Sinorhizobium meliloti is metabolized into glycine betaine choline + sulfate
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Organism

Organism UniProt Comment Textmining
Sinorhizobium meliloti
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
choline sulfate + H2O
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 Sinorhizobium meliloti choline + sulfate
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choline sulfate + H2O is metabolized into glycine betaine Sinorhizobium meliloti choline + sulfate
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phosphorylcholine + H2O less than 20% activity compared to choline sulfate as substrat Sinorhizobium meliloti choline + phosphate
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