Literature summary for 3.1.6.4 extracted from

Shams, S.; Barazandeh Tehrani, M.; Civallero, G.; Minookherad, K.; Giugliani, R.; Setoodeh, A.; Ashtiani, M.
Diagnosing mucopolysaccharidosis type IV a by the fluorometric assay of N-acetylgalactosamine-6-sulfate sulfatase activity (2017), J. Diabetes Metab. Disord., 16, 37 .

Search for more literature for 3.1.6.4

Application

Application	Comment	Organism
medicine	GALNS activity (nmol/17 h/mg protein) is 0-7.4 in samples from mucopolysaccharidosis type IVA patients, as 19.85-93.7 in their parents and as 38.4-164 in the healthy controls. Statistically significant differences are observed between the three groups in terms of enzyme activity. There are no significant differences in enzyme activity by age. The female subjects in both the patient and parents groups show lower enzyme activity compared to the male subjects	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P34059	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood	heparinized blood samples	Homo sapiens	-
leukocyte	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4-methylumbelliferyl-beta-D-galactoside-6-sulfate + H2O	-	Homo sapiens	4-methylumbelliferyl-beta-D-galactoside + sulfate	-	?

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Release 2023.1 (January 2023)