Inhibitors | Comment | Organism | Structure |
---|---|---|---|
6-Sulfated heptasaccharides | strong | Homo sapiens | |
6-Sulfated pentasaccharides | strong | Homo sapiens | |
chondroitin 4-sulfate | slight | Homo sapiens | |
Chondroitin 6-sulfate tetrasaccharide | slight | Homo sapiens | |
dermatan sulfate | slight | Homo sapiens | |
heparin | slight | Homo sapiens | |
hyaluronic acid | slight | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.12 | - |
N-acetylgalactosamine 6-sulfate-beta(1-4)glucuronic acid-beta(1-3)-N-acetylgalactosaminitol 6-sulfate | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
85000 | - |
x * 85000, SDS-PAGE | Homo sapiens |
90000 | - |
gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
placenta | - |
Homo sapiens | - |
skin | fibroblast | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.000653 | - |
enzyme from fibroblasts | Homo sapiens |
0.00073 | - |
enzyme from placenta | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | does not hydrolyze sulfate from N-acetylglucosamine 6-sulfate | Homo sapiens | ? | - |
? | |
N-acetylgalactosamine 6-sulfate-beta(1-4)glucuronic acid-beta(1-3)-N-acetylgalactosaminitol 6-sulfate + H2O | sulfate is hydrolyzed only from the non-reducing terminal | Homo sapiens | sulfate + ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 85000, SDS-PAGE | Homo sapiens |