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Literature summary for 3.1.6.2 extracted from

  • Sato, R.; Suzuki, T.; Katayose, Y.; Miura, K.; Shiiba, K.; Tateno, H.; Miki, Y.; Akahira, J.; Kamogawa, Y.; Nagasaki, S.; Yamamoto, K.; Ii, T.; Egawa, S.; Evans, D.B.; Unno, M.; Sasano, H.
    Steroid sulfatase and estrogen sulfotransferase in colon carcinoma: regulators of intratumoral estrogen concentrations and potent prognostic factors (2009), Cancer Res., 69, 914-922.
    View publication on PubMed

Application

Application Comment Organism
medicine patients with no STS but estrogen sulfotransferase activity (-/+) have better clinical prognosis than all other activity pairs of these enzymes (+/-, +/+, -/-) Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Homo sapiens 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
estrone sulfate + H2O Homo sapiens
-
estrone + sulfate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
colon carcinoma cells
-

Source Tissue

Source Tissue Comment Organism Textmining
colonic cancer cell immunohistochemistry: STS activity in 60% and 61% of patients with colon carcinoma, patients with no STS but estrogen sulfotransferase activity (-/+) have better clinical prognosis than all other activity pairs of these enzymes (+/-, +/+, -/-) Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
estrone sulfate + H2O
-
Homo sapiens estrone + sulfate
-
?

Synonyms

Synonyms Comment Organism
steroid sulfatase
-
Homo sapiens
STS
-
Homo sapiens