Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Triton X-100 | activates | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Bos taurus | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
38000 | - |
alpha2,beta2, 2 * 57000 + 2 * 38000, two 57 kDa catalytic and two 38 kDa regulatory subunits, SDS-PAGE | Bos taurus |
57000 | - |
alpha2,beta2, 2 * 57000 + 2 * 38000, two 57 kDa catalytic and two 38 kDa regulatory subunits, SDS-PAGE | Bos taurus |
180000 | - |
gel filtration, in the presence of Triton X-100 | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Bos taurus | NSS likely plays a key role in the regulation of the GABA-A receptor | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
2-2.5 years old females | - |
Purification (Comment) | Organism |
---|---|
99.3fold | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.000002961 | - |
- |
Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dehydroepiandrosterone sulfate + H2O | - |
Bos taurus | dehydroepiandrosterone + sulfate | - |
? | |
additional information | NSS likely plays a key role in the regulation of the GABA-A receptor | Bos taurus | ? | - |
? | |
pregnenolone sulfate + H2O | - |
Bos taurus | pregnenolone + sulfate | - |
? |
Subunits | Comment | Organism |
---|---|---|
heterotetramer | alpha2,beta2, 2 * 57000 + 2 * 38000, two 57 kDa catalytic and two 38 kDa regulatory subunits, SDS-PAGE | Bos taurus |
Synonyms | Comment | Organism |
---|---|---|
neurosteroid sulfatase | - |
Bos taurus |
NSS | - |
Bos taurus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Bos taurus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Bos taurus |