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Literature summary for 3.1.6.2 extracted from

  • Rhodes, M.E.; Li, P.K.; Burke, A.M.; Johnson, D.A.
    Enhanced plasma DHEAS, brain acetylcholine and memory mediated by steroid sulfatase inhibition (1997), Brain Res., 773, 28-32.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
(p-O-sulfamoyl)-N-tetradecanoyl tyramine DU-14, in vivo, increase in hippocampal acetylcholine Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
steroid sulfates + H2O Rattus norvegicus also acts on some related steryl sulfates, phenol sulfates, steroid arylsulfates and steroid alkyl sulfates catalyzed at the same site steroid + sulfate
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Rattus norvegicus
-
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dehydroepiandrosterone 3-sulfate + H2O
-
Rattus norvegicus dehydroepiandrosterone + sulfate
-
?
estrone sulfate + H2O
-
Rattus norvegicus estrone + sulfate
-
?
steroid sulfates + H2O also acts on some related steryl sulfates, phenol sulfates, steroid arylsulfates and steroid alkyl sulfates catalyzed at the same site Rattus norvegicus steroid + sulfate
-
?