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Literature summary for 3.1.6.2 extracted from

  • Shankaran, R.; Ameen, M.; Daniel, W.L.; Davidson, R.G.; Chang, P.L.
    Characterization of arylsulfatase C isozymes from human liver and placenta (1991), Biochim. Biophys. Acta, 1078, 251-257.
    View publication on PubMed
Search for more literature for 3.1.6.2

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.27
-
 methylumbelliferyl sulfate s-form Homo sapiens
0.58
-
 methylumbelliferyl sulfate f-form Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
183000
-
 placenta, s-form, gel filtration, two isoforms s- and f-form Homo sapiens
200000
-
 liver, f-form, gel filtration, two isoforms s- and f-form Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
steroid sulfates + H2O Homo sapiens also acts on some related steryl sulfates, phenol sulfates, steroid arylsulfates and steroid alkyl sulfates catalyzed at the same site steroid + sulfate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-
placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-methylumbelliferyl sulfate + H2O both s-form and f-form Homo sapiens 4-methylumbelliferone + sulfate
-
 ?
cholesterol 3-sulfate + H2O only s-form Homo sapiens cholesterol + sulfate
-
 ?
dehydroepiandrosterone 3-sulfate + H2O only s-form Homo sapiens dehydroepiandrosterone + sulfate
-
 ?
estrone sulfate + H2O only s-form Homo sapiens estrone + sulfate
-
 ?
steroid sulfates + H2O also acts on some related steryl sulfates, phenol sulfates, steroid arylsulfates and steroid alkyl sulfates catalyzed at the same site Homo sapiens steroid + sulfate
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
50
-
 f-form: 50% loss of activity Homo sapiens
57
-
 s-form: 50% loss of activity Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5 5.5
-
 Homo sapiens
6.9
-
 f-form Homo sapiens
7.3 7.5
-
 Homo sapiens