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Literature summary for 3.1.6.2 extracted from

  • Dibbelt, L.; Kuss, E.
    Human placental steroid-sulfatase. Kinetics of the in-vitro hydrolysis of dehydroepiandrosterone 3-sulfate and of 16 alpha-hydroxydehydroepiandrosterone 3-sulfate (1983), Hoppe-Seyler's Z. Physiol. Chem., 364, 187-191.
    View publication on PubMed
Search for more literature for 3.1.6.2

Inhibitors

Inhibitors Comment Organism Structure
16alpha-hydroxydehydroepiandrosterone competitive to dihydroepiandrosterone Homo sapiens
dehydroepiandrosterone competitive to 16alpha-hydroxydehydroepiandrosterone Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.003
-
 dehydroepiandrosterone 3-sulfate
-
 Homo sapiens
0.008
-
 dehydroepiandrosterone 3-sulfate
-
 Homo sapiens
0.02
-
 16alpha-hydroxydehydroepiandrosterone 3-sulfate
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
steroid sulfates + H2O Homo sapiens also acts on some related steryl sulfates, phenol sulfates, steroid arylsulfates and steroid alkyl sulfates catalyzed at the same site steroid + sulfate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
16alpha-hydroxydehydroepiandrosterone 3-sulfate + H2O
-
 Homo sapiens 16alpha-hydroxydehydroepiandrosterone + sulfate
-
 ?
dehydroepiandrosterone 3-sulfate + H2O
-
 Homo sapiens dehydroepiandrosterone + sulfate
-
 ?
steroid sulfates + H2O also acts on some related steryl sulfates, phenol sulfates, steroid arylsulfates and steroid alkyl sulfates catalyzed at the same site Homo sapiens steroid + sulfate
-
 ?