Inhibitors | Comment | Organism | Structure |
---|---|---|---|
NaCl | due to Cl- | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Homo sapiens | 5764 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
95000 | - |
form A, B, gel filtration | Homo sapiens |
132000 | - |
form C, gel filtration | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dermatan sulfate + H2O | Homo sapiens | - |
dermatan + sulfate | - |
? | |
heparan sulfate + H2O | Homo sapiens | - |
dermatan + sulfate | - |
? | |
heparin + H2O | Homo sapiens | - |
desulfated heparin + sulfate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
multiple forms: A, B, C | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | contains sialic acid residues | Homo sapiens |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
amniotic fluid | - |
Homo sapiens | - |
kidney | contains only form A | Homo sapiens | - |
placenta | - |
Homo sapiens | - |
serum | distribution of the forms A, B and C in body fluids | Homo sapiens | - |
serum | contains only form C | Homo sapiens | - |
urine | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dermatan sulfate + H2O | - |
Homo sapiens | dermatan + sulfate | - |
? | |
heparan sulfate + H2O | - |
Homo sapiens | dermatan + sulfate | - |
? | |
heparin + H2O | - |
Homo sapiens | desulfated heparin + sulfate | - |
? | |
O-(alpha-L-idopyranosyluronic acid 2-sulfate)-(1-4)-2,5-anhydro-D-mannitol 6-sulfate + H2O | - |
Homo sapiens | O-(alpha-L-idopyranosyluronic acid)-(1-4)-2,5-anhydro-D-mannitol 6-sulfate + sulfate | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
4.1 | 5.3 | form C, depending on ionic strength | Homo sapiens |
4.4 | 5.3 | form B, depending on ionic strength | Homo sapiens |
4.5 | 5.3 | form A, depending on ionic strength | Homo sapiens |