Application | Comment | Organism |
---|---|---|
medicine | leukocytes of patients with cerebral palsy show lower enzyme activity as compared to control. Km value for 4-nitrocatechol sulfate in patients' leukocytes is about 0.26 mM, in control 0.21 mM, whereas Vmax value in patients reaches only 58% of healthy control. All investigated patients reveal presence of the most common mutations associated with enzyme pseudodeficiency | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.21 | - |
4-nitrocatechol sulfate | pH 5.0, 37°C, wild-type | Homo sapiens | |
0.26 | - |
4-nitrocatechol sulfate | pH 5.0, 37°C, patient with cerebral palsy | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
patients with cerebral palsy | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leukocyte | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrocatechol sulfate + H2O | - |
Homo sapiens | 4-nitrocatechol + sulfate | - |
? |