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Literature summary for 3.1.5.1 extracted from

  • Quirk, S.; Bessman, M.J.
    dGTP triphosphohydrolase, a unique enzyme confined to members of the family Enterobacteriaceae (1991), J. Bacteriol., 173, 6665-6669.
    View publication on PubMedView publication on EuropePMC

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
230000
-
gel filtration Escherichia coli
230000
-
enzyme is present only in enteric bacteria Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dGTP + H2O Salmonella enterica subsp. enterica serovar Typhimurium
-
deoxyguanosine + triphosphate
-
?
dGTP + H2O Escherichia coli
-
deoxyguanosine + triphosphate
-
?
dGTP + H2O Klebsiella aerogenes
-
deoxyguanosine + triphosphate
-
?
dGTP + H2O Serratia marcescens
-
deoxyguanosine + triphosphate
-
?
dGTP + H2O Proteus mirabilis
-
deoxyguanosine + triphosphate
-
?
dGTP + H2O Citrobacter freundii
-
deoxyguanosine + triphosphate
-
?
dGTP + H2O Hafnia alvei
-
deoxyguanosine + triphosphate
-
?
dGTP + H2O Yersinia enterocolitica
-
deoxyguanosine + triphosphate
-
?
dGTP + H2O Klebsiella oxytoca
-
deoxyguanosine + triphosphate
-
?
dGTP + H2O Cedecea davisae
-
deoxyguanosine + triphosphate
-
?
dGTP + H2O Salmonella enterica subsp. enterica serovar Gallinarum
-
deoxyguanosine + triphosphate
-
?
dGTP + H2O Shigella boydii
-
deoxyguanosine + triphosphate
-
?

Organism

Organism UniProt Comment Textmining
Cedecea davisae
-
-
-
Citrobacter freundii
-
-
-
Escherichia coli
-
-
-
Hafnia alvei
-
-
-
Klebsiella aerogenes
-
-
-
Klebsiella oxytoca
-
-
-
Proteus mirabilis
-
-
-
Salmonella enterica subsp. enterica serovar Gallinarum
-
-
-
Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-
Serratia marcescens
-
-
-
Shigella boydii
-
-
-
Yersinia enterocolitica
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Escherichia coli
partial Salmonella enterica subsp. enterica serovar Typhimurium
partial Klebsiella aerogenes
partial Proteus mirabilis
partial Citrobacter freundii
partial Hafnia alvei
partial Yersinia enterocolitica
partial Klebsiella oxytoca
partial Cedecea davisae
partial Salmonella enterica subsp. enterica serovar Gallinarum
partial, no precipitation with nucleic acids Serratia marcescens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dGTP + H2O
-
Salmonella enterica subsp. enterica serovar Typhimurium deoxyguanosine + triphosphate
-
?
dGTP + H2O
-
Escherichia coli deoxyguanosine + triphosphate
-
?
dGTP + H2O
-
Klebsiella aerogenes deoxyguanosine + triphosphate
-
?
dGTP + H2O
-
Serratia marcescens deoxyguanosine + triphosphate
-
?
dGTP + H2O
-
Proteus mirabilis deoxyguanosine + triphosphate
-
?
dGTP + H2O
-
Citrobacter freundii deoxyguanosine + triphosphate
-
?
dGTP + H2O
-
Hafnia alvei deoxyguanosine + triphosphate
-
?
dGTP + H2O
-
Yersinia enterocolitica deoxyguanosine + triphosphate
-
?
dGTP + H2O
-
Klebsiella oxytoca deoxyguanosine + triphosphate
-
?
dGTP + H2O
-
Cedecea davisae deoxyguanosine + triphosphate
-
?
dGTP + H2O
-
Salmonella enterica subsp. enterica serovar Gallinarum deoxyguanosine + triphosphate
-
?
dGTP + H2O
-
Shigella boydii deoxyguanosine + triphosphate
-
?
dGTP + H2O highly specific for Salmonella enterica subsp. enterica serovar Typhimurium deoxyguanosine + triphosphate
-
?
dGTP + H2O highly specific for Escherichia coli deoxyguanosine + triphosphate
-
?
dGTP + H2O highly specific for Klebsiella aerogenes deoxyguanosine + triphosphate
-
?
dGTP + H2O highly specific for Serratia marcescens deoxyguanosine + triphosphate
-
?
dGTP + H2O highly specific for Proteus mirabilis deoxyguanosine + triphosphate
-
?
dGTP + H2O highly specific for Citrobacter freundii deoxyguanosine + triphosphate
-
?
dGTP + H2O highly specific for Hafnia alvei deoxyguanosine + triphosphate
-
?
dGTP + H2O highly specific for Yersinia enterocolitica deoxyguanosine + triphosphate
-
?
dGTP + H2O highly specific for Klebsiella oxytoca deoxyguanosine + triphosphate
-
?
dGTP + H2O highly specific for Cedecea davisae deoxyguanosine + triphosphate
-
?
dGTP + H2O highly specific for Salmonella enterica subsp. enterica serovar Gallinarum deoxyguanosine + triphosphate
-
?
dGTP + H2O highly specific for Shigella boydii deoxyguanosine + triphosphate
-
?
dGTP + H2O no activity on dGDP Escherichia coli deoxyguanosine + triphosphate
-
?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
55 60
-
Salmonella enterica subsp. enterica serovar Typhimurium
55 60
-
Klebsiella aerogenes
55 60
-
Serratia marcescens
55 60
-
Proteus mirabilis
55 60
-
Citrobacter freundii
55 60
-
Hafnia alvei
55 60
-
Yersinia enterocolitica
55 60
-
Klebsiella oxytoca
55 60
-
Cedecea davisae
55 60
-
Salmonella enterica subsp. enterica serovar Gallinarum
55 60
-
Shigella boydii
55 60 full activity after 1 h Escherichia coli