Literature summary for 3.1.4.54 extracted from

Correa, F.; De Laurentiis, A.; Franchi, A.M.
Ethanol downregulates N-acyl phosphatidylethanolamine-phospholipase D expression in BV2 microglial cells via epigenetic mechanisms (2016), Eur. J. Pharmacol., 786, 224-233 .

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Application

Application	Comment	Organism
medicine	effects of acute ethanol exposure to murine BV2 microglial cells. Ethanol downregulates microglial NAPE-PLD expression by activating cAMP/PKA and ERK1/2. Ethanol induces an increase in histone acetyltransferase activity which leads to higher levels of acetylation of histone H3	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	Q8BH82	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
BV-2 cell	-	Mus musculus	-

Expression

Organism	Comment	Expression
Mus musculus	ethanol downregulates microglial NAPE-PLD expression by activating cAMP/PKA and ERK1/2	down

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Release 2023.1 (January 2023)