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Literature summary for 3.1.4.53 extracted from

  • Pooley, L.; Shakur, Y.; Rena, G.; Houslay, M.D.
    Intracellular localization of the PDE4A cAMP-specific phosphodiesterase splice variant RD1 (RNPDE4A1A) in stably transfected human thyroid carcinoma FTC cell lines (1997), Biochem. J., 321 (Pt 1), 177-185.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
cells of two human follicular thyroid carcinoma cell lines (FTC133, FTC236) are stably transfected with a cDNA encoding the PDE4A cAMP-specific phosphodiesterase (PDE) splice variant RD1 (RNPDE4A1A) so as to generate the cloned cell lines, FTC133A and FTC236A Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi apparatus PDE4A splice variant RD1 contains a membrane-association signal which allows the targeted expression of RD1 within the Golgi complex of human follicular thyroid carcinoma cell lines FTC133 and FTC236 Rattus norvegicus 5794
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus P54748
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Source Tissue

Source Tissue Comment Organism Textmining
follicular thyroid carcinoma cell line FTC133 and FTC236 Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
adenosine 3',5'-cyclic phosphate + H2O
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Rattus norvegicus adenosine 5'-phosphate
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Synonyms

Synonyms Comment Organism
PDE4A cAMP-specific phosphodiesterase splice variant RD1
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Rattus norvegicus
RNPDE4A1A
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Rattus norvegicus