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Literature summary for 3.1.4.53 extracted from

  • Oelke, M.; Hedlund, P.; Albrecht, K.; Ellinghaus, P.; Stief, C.G.; Jonas, U.; Andersson, K.E.; Uckert, S.
    Expression of cAMP and cGMP-phosphodiesterase isoenzymes 3, 4, and 5 in the human clitoris: immunohistochemical and molecular biology study (2006), Urology, 67, 1111-1116.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens PDE4 may be involved in the cyclic nucleotide-mediated control of smooth muscle tone ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Homo sapiens
-
 isoform PDE4
-

Source Tissue

Source Tissue Comment Organism Textmining
clitoris PDE4 is observed in the nonvascular smooth musculature of the corpus cavernosum clitoris, sinusoidal endothelial and subendothelial layers, and nerve fibers innervating the tissue Homo sapiens
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clitoris presence of isoform PDE4 in nonvascular smooth musculature of the corpus carnosum, in sinusoidal endothelial and subendothelial layers, and nerve fiber innervating the tissue Homo sapiens
-
corpus cavernosum presence of isoform PDE4 in nonvascular smooth musculature of the corpus carnosum Homo sapiens
-
endothelial cell sinusoidal endothelial and subendothelialn layer of clitoris, presence of isoform PDE4 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PDE4 may be involved in the cyclic nucleotide-mediated control of smooth muscle tone Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
PDE4
-
 Homo sapiens