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BRENDA support

Literature summary for 3.1.4.53 extracted from

  • Giorgi, M.; Modica, A.; Pompili, A.; Pacitti, C.; Gasbarri, A.
    The induction of cyclic nucleotide phosphodiesterase 4 gene (PDE4D) impairs memory in a water maze task (2004), Behav. Brain Res., 154, 99-106.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
DC-TA 46 the inhibitor affects memory retention in a visible/hidden-platform water maze task. This memory impairment can be correlated to the decrease of cAMP nucleotide, due to the induction of a PDE4D cAMP-specific PDE isoform Rattus norvegicus
rolipram the inhibitor affects memory retention in a visible/hidden-platform water maze task. This memory impairment can be correlated to the decrease of cAMP nucleotide, due to the induction of a PDE4D cAMP-specific PDE isoform Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
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Rattus norvegicus
-