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Literature summary for 3.1.4.43 extracted from

  • Dawson, R.M.C.; Hemington, N.
    A phosphodiesterase in rat kidney cortex that hydrolyses glycerylphosphorylinositol (1977), Biochem. J., 162, 241-245.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.4.43

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
 Rattus norvegicus
Mg2+
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.2
-
 sn-glycero-3-phospho-1-inositol
-
 Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ 2-3 mM, stimulates Rattus norvegicus
Mn2+ limited stimulation Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
sn-glycero-3-phospho-1-inositol + H2O Rattus norvegicus catabolism of phosphatidylinositol ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney outer cortex, brush border of proximal tubules Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-myo-inositol 1,2-cyclic phosphate + H2O
-
 Rattus norvegicus 1D-myo-inositol 1-phosphate + H+
-
 ?
sn-glycero-3-phospho-1-inositol
-
 Rattus norvegicus glycerol + inositol cyclic phosphate the enzyme can act as a cyclizing phosphotransferase ?
sn-glycero-3-phospho-1-inositol + H2O
-
 Rattus norvegicus glycerol + inositol 1-phosphate
-
 ?
sn-glycero-3-phospho-1-inositol + H2O catabolism of phosphatidylinositol Rattus norvegicus ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.8 8.6
-
 Rattus norvegicus