Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
sphingomyelin + H2O | Loxosceles intermedia | - |
ceramide phosphate + choline | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Loxosceles intermedia | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Loxosceles intermedia | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
sphingomyelin + H2O | - |
Loxosceles intermedia | ceramide phosphate + choline | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SMase D | - |
Loxosceles intermedia |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is a toxic component of Loxosceles venom that activates human blood leukocytes in a partially complement-dependent manner, which can contribute to the systemic inflammation that follows envenomation by the spider | Loxosceles intermedia |