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Literature summary for 3.1.4.4 extracted from

  • Pleskot, R.; Potocky, M.; Pejchar, P.; Linek, J.; Bezvoda, R.; Martinec, J.; Valentova, O.; Novotna, Z.; Zarsky, V.
    Mutual regulation of plant phospholipase D and the actin cytoskeleton (2010), Plant J., 62, 494-507.
    View publication on PubMed
Search for more literature for 3.1.4.4

Protein Variants

Protein Variants Comment Organism
additional information antisense-mediated knockdown of tobacco pollen PLDs results in inhibition of pollen tube growth Nicotiana tabacum
N232A site-directed mutagenesis of isozyme PLDbeta1, leads to reduced actin and G-protein binding Nicotiana tabacum
N323A/T382A site-directed mutagenesis of isozyme PLDbeta1, leads to reduced actin and G-protein binding Nicotiana tabacum
T382A site-directed mutagenesis of isozyme PLDbeta1, leads to reduced actin and G-protein binding Nicotiana tabacum

Inhibitors

Inhibitors Comment Organism Structure
additional information no inhibition by tert-butanol; no inhibition by tert-butanol; no inhibition by tert-butanol Nicotiana tabacum
n-butanol PLD inhibition disrupts the actin cytoskeleton in tobacco pollen tubes; PLD inhibition disrupts the actin cytoskeleton in tobacco pollen tubes; PLD inhibition disrupts the actin cytoskeleton in tobacco pollen tubes Nicotiana tabacum

Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Nicotiana tabacum ability of PLD-generated phosphatidic acid to control actin polymerization and the reciprocal ability of actin to specifically modulate PIP2-dependent PLD, PLDbeta, activity through direct interaction ?
-
 ?

Organism

Organism UniProt Comment Textmining
Nicotiana tabacum D7P5D9 cv. Samsun and Bright Yellow 2, different isozymes
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Nicotiana tabacum D7P5E0 cv. Samsun and Bright Yellow 2, isozyme PLDbeta1
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Nicotiana tabacum D7P5E1 cv. Samsun and Bright Yellow 2, isozyme PLDdelta
-

Source Tissue

Source Tissue Comment Organism Textmining
cell culture from cv. Bright Yellow 2 Nicotiana tabacum
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additional information semi-quantitative PCR analysis of PLD expression and tissue distribvution Nicotiana tabacum
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pollen from cv. Samsun Nicotiana tabacum
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pollen tube
-
 Nicotiana tabacum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information ability of PLD-generated phosphatidic acid to control actin polymerization and the reciprocal ability of actin to specifically modulate PIP2-dependent PLD, PLDbeta, activity through direct interaction Nicotiana tabacum ?
-
 ?
additional information enhanced binding of isozyme PLDbeta1 to actin is mediated by amino acid residues Asn323 and Thr382 Nicotiana tabacum ?
-
 ?

Synonyms

Synonyms Comment Organism
PIP2-independent PLD
-
 Nicotiana tabacum
PLD
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 Nicotiana tabacum
PLDalpha
-
 Nicotiana tabacum
PLDalpha3
-
 Nicotiana tabacum
PLDbeta
-
 Nicotiana tabacum
PLDbeta1
-
 Nicotiana tabacum
PLDdelta
-
 Nicotiana tabacum

General Information

General Information Comment Organism
malfunction PLD inhibition disrupts the actin cytoskeleton in tobacco pollen tubes, with severe disorganization of actin, both in the apex and in the shank Nicotiana tabacum
physiological function PLD activity controls the structure of the actin cytoskeleton in tobacco pollen tubes, actin forms affect differently the activity of distinct tobacco C2 PLDs, overview Nicotiana tabacum