Activating Compound | Comment | Organism | Structure |
---|---|---|---|
L-ascorbic acid | activates the lipid signaling enzyme PLD at pharmacological doses, 5 mM, in the bovine lung microvascular endothelial cells, with modulation of PLD activation by phospholipase A2, PLA2. Antioxidants attenuate vitamin C-induced PLA2 , e.g. N-acetylcysteine, propyl gallate, or enzyme catalase activation | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Bos taurus | PLD also performs transphosphatidylation using 1-butanol as phosphatidyl acceptor, the transphosphatidylation reaction is an index of PLD activity in intact cells | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lung | microvascular endothelial cells | Bos taurus | - |
vascular endothelial cell | - |
Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
PLD transphosphatidylation activity at different conditions, overview | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | PLD also performs transphosphatidylation using 1-butanol as phosphatidyl acceptor, the transphosphatidylation reaction is an index of PLD activity in intact cells | Bos taurus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PLD | - |
Bos taurus |