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Literature summary for 3.1.4.39 extracted from
- Lysophosphatidylmethanol is a pan lysophosphatidic acid receptor agonist and is produced by autotaxin in blood (2009), J. Biochem., 146, 283-293.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| T209A | catalytically inactive | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood plasma | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| lysophosphatidylcholine + H2O | - |
Mus musculus | lysophosphatidic acid + choline | - |
? |  |
| additional information | when recombinant ATX is incubated with ysophosphatidylcholine in the presence of methanol, both lysophosphatidylmethanol and lysophosphatidic acid are produced with a ratio of 1:10, showing that ATX has transphosphatidylation activity in addition to its lysophospholipase D activity | Mus musculus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ATX | - |
Mus musculus |
| autotaxin | - |
Mus musculus |
| lysophospholipase D | - |
Mus musculus |
| lysoPLD | - |
Mus musculus |
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