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Literature summary for 3.1.4.39 extracted from

  • Jansen, S.; Stefan, C.; Creemers, J.W.; Waelkens, E.; Van Eynde, A.; Stalmans, W.; Bollen, M.
    Proteolytic maturation and activation of autotaxin (NPP2), a secreted metastasis-enhancing lysophospholipase D (2005), J. Cell Sci., 118, 3081-3089.
    View publication on PubMed
Search for more literature for 3.1.4.39

Application

Application Comment Organism
medicine stimulates cell proliferation, cell motility and angiogenesis Rattus norvegicus

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli DH5alpha Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Rattus norvegicus
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
120000
-
 immunoblotting, lysate and medium Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification proteolytically processed protein is secreted, secreted and cell-associated NPP2 are differently glycosylated Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
lysophosphatidylcholine + H2O
-
 Rattus norvegicus lysophosphatidic acid + choline
-
 ?
sphingosylphosphorylcholine + H2O
-
 Rattus norvegicus sphingosine-1-phosphate + choline
-
 ?

Synonyms

Synonyms Comment Organism
ATX
-
 Rattus norvegicus
autotaxin
-
 Rattus norvegicus
NPP2
-
 Rattus norvegicus