Literature summary for 3.1.4.39 extracted from

Song, J.; Clair, T.; Noh, J.H.; Eun, J.W.; Ryu, S.Y.; Lee, S.N.; Ahn, Y.M.; Kim, S.Y.; Lee, S.H.; Park, W.S.; Yoo, N.J.; Lee, J.Y.; Nam, S.W.
Autotaxin (lysoPLD/NPP2) protects fibroblasts from apoptosis through its enzymatic product, lysophosphatidic acid, utilizing albumin-bound substrate (2005), Biochem. Biophys. Res. Commun., 337, 967-975.

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Application

Application	Comment	Organism
medicine	survival factor, preventing serum-deprivation induced apoptosis in fibroblasts through extracellular activation of LPA signaling pathway	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
-	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
extracellular	-	Homo sapiens	-	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
with and without His-tag	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
lysophosphatidylcholine + H2O	albumin-bound lipid	Homo sapiens	lysophosphatidic acid + choline	-	?

Synonyms

Synonyms	Comment	Organism
ATX	-	Homo sapiens
autotaxin	-	Homo sapiens
lysophospholipase D	-	Homo sapiens
lysoPLD/NPP2	-	Homo sapiens

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Release 2023.1 (January 2023)