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Literature summary for 3.1.4.37 extracted from

  • Jackson, E.K.; Menshikova, E.V.; Mi, Z.; Verrier, J.D.; Bansal, R.; Janesko-Feldman, K.; Jackson, T.C.; Kochanek, P.M.
    Renal 2',3'-cyclic nucleotide 3'-phosphodiesterase is an important determinant of AKI severity after ischemia-reperfusion (2016), J. Am. Soc. Nephrol., 27, 2069-2081 .
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
nucleoside 2',3'-cyclic phosphate + H2O Mus musculus
-
 nucleoside 2'-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2',3'-cAMP + H2O
-
 Mus musculus 2'-AMP
-
 ?
nucleoside 2',3'-cyclic phosphate + H2O
-
 Mus musculus nucleoside 2'-phosphate
-
 ?

Synonyms

Synonyms Comment Organism
2',3'-cyclic nucleotide 3'-phosphodiesterase
-
 Mus musculus
CNPase
-
 Mus musculus

General Information

General Information Comment Organism
malfunction enzyme deletion attenuates ischemia-reperfusion-induced acute kidney injury, in part by accelerating autophagy with targeted removal of damaged mitochondria Mus musculus