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Literature summary for 3.1.4.37 extracted from

  • Lee, J.; Gravel, M.; Zhang, R.; Thibault, P.; Braun, P.E.
    Process outgrowth in oligodendrocytes is mediated by CNP, a novel microtubule assembly myelin protein (2005), J. Cell Biol., 170, 661-673.
    View publication on PubMedView publication on EuropePMC
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Protein Variants

Protein Variants Comment Organism
additional information enzyme overexpression induces dramatic morphology changes in both glial and nonglial cells, resulting in microtubule and F-actin reorganization and formation of branched processes. Cultured oligodendrocytes from enzyme-deficient mice extend smaller outgrowths with less arborized processes Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus enzyme is involved in mediating process formation in oligodendrocytes ?
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 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme is involved in mediating process formation in oligodendrocytes Mus musculus ?
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 ?

Subunits

Subunits Comment Organism
More enzyme interacts with tubulin, binding preferentially to tubulin heterodimers and inducing assembly of mircotubulues by cooperation with tubulin Mus musculus