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Literature summary for 3.1.4.35 extracted from

  • Zou, P.; Hou, P.; Oh, S.S.; Ge, X.; Bloodworth, B.C.; Low, M.Y.; Koh, H.L.
    Identification of benzamidenafil, a new class of phosphodiesterase-5 inhibitor, as an adulterant in a dietary supplement (2008), J. Pharm. Biomed. Anal., 47, 255-259.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
benzamidenafil i.e. N-(3,4-dimethoxy benzyl)-2-[[(1R,S)-2-hydroxy-1-methylethyl]amino]-5-nitrobenzamide, potent and specific inhibitor of PDE-5 Homo sapiens
sildenafil
-
 Homo sapiens
tadalafil
-
 Homo sapiens
vardenafil
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Synonyms

Synonyms Comment Organism
PDE-5
-
 Homo sapiens
PDE-6
-
 Homo sapiens
phosphodiesterase-5
-
 Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0000011
-
 PDE-5, pH and temperature not specified in the publication Homo sapiens benzamidenafil
0.0000043
-
 PDE-5, pH and temperature not specified in the publication Homo sapiens sildenafil
0.000015
-
 PDE-6, pH and temperature not specified in the publication Homo sapiens sildenafil
0.00002
-
 PDE-6, pH and temperature not specified in the publication Homo sapiens benzamidenafil