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Literature summary for 3.1.4.35 extracted from
- Acute hemodynamic effects of intravenous sildenafil citrate in congestive heart failure: comparison of phosphodiesterase type-3 and -5 inhibition (2009), J. Heart Lung Transplant., 28, 676-682.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | in end-stage congestive cardiac failure, intravenous sildenafil causes reduction in systemic and pulmonary vascular resistance, sildenafil has a suitable hemodynamic profile for testing of reversibility of secondary pulmonary hypertension in congestive cardiac failure | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| sildenafil | - |
Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PDE5 | - |
Homo sapiens |
| phosphodiesterase type-5 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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