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Literature summary for 3.1.4.35 extracted from
- Expression and activity of cGMP-dependent phosphodiesterases is up-regulated by lipopolysaccharide (LPS) in rat peritoneal macrophages (2007), Biochim. Biophys. Acta, 1773, 209-218.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Rattus norvegicus | 5737 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
isoform PDE5 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| peritoneal macrophage | in freshly isolated peritoneal exudate macrophage, isoform PDE5 is expressed. After 24h of cultures, PDE5 is no longer present | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cGMP + H2O | - |
Rattus norvegicus | 5'-GMP | - |
? |  |
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Release 2023.1 (January 2023)
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