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Literature summary for 3.1.4.35 extracted from

  • Belmonte, A.; Ticconi, C.; Dolci, S.; Giorgi, M.; Zicari, A.; Lenzi, A.; Jannini, E.A.; Piccione, E.
    Regulation of phosphodiesterase 5 expression and activity in human pregnant and non-pregnant myometrial cells by human chorionic gonadotropin (2005), J. Soc. Gynecol. Investig., 12, 570-577.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
sildenafil
-
Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens human chorionic gonadotropin reduces PDE5 expression and enzyme activity in smooth muscle cells, possibly through a pathway involving cAMP ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
myometrium pregnant and non-pregnant Homo sapiens
-
smooth muscle cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information human chorionic gonadotropin reduces PDE5 expression and enzyme activity in smooth muscle cells, possibly through a pathway involving cAMP Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
PDE5
-
Homo sapiens