Literature summary for 3.1.4.3 extracted from

Shimizu, T.; Tanaka, K.; Nakamura, K.; Taniuchi, K.; Yokotani, K.
Brain phospholipase C, diacylglycerol lipase and monoacylglycerol lipase are involved in (+/-)-epibatidine-induced activation of central adrenomedullary outflow in rats (2012), Eur. J. Pharmacol., 691, 93-102.

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Inhibitors

Inhibitors	Comment	Organism	Structure
1-[6-[[(17beta)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione	i.e. U-73122, a phospholipase C inhibitor	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Rattus norvegicus	-

General Information

General Information	Comment	Organism
physiological function	brain phospholipase C is involved in (+/-)-epibatidine-induced activation of central adrenomedullary outflow in rats, overview. (+/-)-epibatidine activates spinally projecting neurons expressing monoacylglycerol lipase in the rat hypothalamic paraventricular nucleus, a control center of central sympatho-adrenomedullary outflow	Rattus norvegicus

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Release 2023.1 (January 2023)