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Literature summary for 3.1.4.3 extracted from

  • Spadaro, F.; Cecchetti, S.; Sanchez, M.; Ausiello, C.M.; Podo, F.; Ramoni, C.
    Expression and role of phosphatidylcholine-specific phospholipase C in human NK and T lymphocyte subsets (2006), Eur. J. Immunol., 36, 3277-3287.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane high level of enzyme expression on the outer membrane surface of natural killer cells. Enzyme expression level on the membrane closely correlates with that of the CD16 receptor Homo sapiens 16020
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
B-lymphocyte low level of enzyme expression Homo sapiens
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gamma delta T-lymphocyte low level of enzyme expression in some cells Homo sapiens
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lymph substantial intracellular amounts of isoform PC-PLC in all lymphoid subsets Homo sapiens
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additional information no detection of enzyme expression on CD4+ and CD8+ T lymphocytes Homo sapiens
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natural killer cell high level of enzyme expression on the outer membrane surface. Identification of two subsets of cells, CD56dimPC-PLCbright and CD56brightPC-PLClow/-, corresponding to distinct subsets with cytolytic and immunoregulatory function. Enzyme expression level on the membrane closely correlates with that of the CD16 receptor Homo sapiens
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