Application | Comment | Organism |
---|---|---|
medicine | chemokine CCL2, i.e. MCP-1, enhances HIV-1 replication. Enzyme isoform PC-PLC is activated by HIV-1 R5 gp120 interaction with CCR5 and is required for NF-kB-mediated CCL2 production triggered by R5 gp120 in monocyte-derived macrophages | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
isoform PC-PLC | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
macrophage | monocyte-derived macrophage, enzyme is activated by HIV-1 R5 gp120 interaction with CCR5 and is required for NF-kB-mediated chemokine CCL2 production triggered by R5 gp120 | Homo sapiens | - |