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BRENDA support

Literature summary for 3.1.4.3 extracted from

  • Barr, A.J.; Ali, H.; Haribabu, B.; Snyderman, R.; Smrcka, A.V.
    Identification of a region at the N-terminus of phospholipase C-b3 that interacts with G protein bg subunits (2000), Biochemistry, 39, 1800-1806.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information construction of a series of fragments, N-terminal Gbetagamma binding region in first 180 amino acids of enzyme, amino acids 150-180 are required for interaction with Gbetagamma, mutations in this region reduce binding capacity and ability to be activated by Gbetagamma Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
isoform PLC-beta3
-