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Literature summary for 3.1.4.2 extracted from

  • Abra, R.M.; Quinn, P.J.
    Some characteristics of sn-glycero 3-phosphocholine diesterases from rat brain (1976), Biochim. Biophys. Acta, 431, 631-639.
    View publication on PubMed
Search for more literature for 3.1.4.2

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
 Rattus sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.6
-
 sn-glycero 3-phosphocholine
-
 Rattus sp.

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome binding to the membrane Rattus sp.
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ fully restored activity if chelating agents used Rattus sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
72000
-
 sucrose density gradient centrifugation, SDS-PAGE analysis Rattus sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
sn-glycero 3-phosphorylcholine + H2O Rattus sp. cellular phosphatidylcholine catabolic pathway ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus sp.
-
-
-

Purification (Commentary)

Purification (Comment) Organism
60-fold purification Rattus sp.

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus sp.
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.001
-
-
 Rattus sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
sn-glycero 3-phosphorylcholine + H2O
-
 Rattus sp. sn-glycerol 3-phosphate + choline
-
 ?
sn-glycero 3-phosphorylcholine + H2O cellular phosphatidylcholine catabolic pathway Rattus sp. ?
-
 ?

Subunits

Subunits Comment Organism
dimer alpha2, 2 * 60000-72000, sucrose density gradient centrifugation and SDS-PAGE Rattus sp.

Synonyms

Synonyms Comment Organism
sn-glycero 3-phosphocholine diesterase
-
 Rattus sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.9
-
-
 Rattus sp.