Any feedback?
Literature summary for 3.1.4.2 extracted from
- GDPD5, a choline-generating enzyme and its novel role in tumor cell migration (2016), Arch. Toxicol., 90, 3143-3144 .
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | enzyme inhibition represents a targeting strategy in the treatment of breast cancer | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| sn-glycero-3-phosphocholine + H2O | Homo sapiens | - |
choline + sn-glycerol 3-phosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q8WTR4 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| breast cancer cell | - |
Homo sapiens | - |
| MCF-7 cell | - |
Homo sapiens | - |
| MDA-MB-231 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| sn-glycero-3-phosphocholine + H2O | - |
Homo sapiens | choline + sn-glycerol 3-phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| EDI3 | isoform | Homo sapiens |
| GDE2 | isoform | Homo sapiens |
| GDPD5 | - |
Homo sapiens |
| GDPD6 | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme drives tumor cell migration | Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
