Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5-(3-cyclopentyloxy-4-methoxy-phenyl)-pyrrolidin-2-one | 50% inhibition at about 0.1 mM | Rattus norvegicus | |
dipyridamole | 50% inhibition at about 0.0002-0.00055 mM | Rattus norvegicus | |
E4021 | 50% inhibition at about 0.0005-0.001 mM | Rattus norvegicus | |
erythro-9-(2-hydroxy-3-nonyl)adenine | 50% inhibition at about 0.1 mM | Rattus norvegicus | |
isobutylmethylxanthine | 50% inhibition at about 0.05 mM | Rattus norvegicus | |
Milrinone | 50% inhibition at about 0.1 mM | Rattus norvegicus | |
vinpocetine | 50% inhibition at about 0.06-0.09 mM | Rattus norvegicus | |
zaprinast | 50% inhibition at about 0.016-0.02 mM | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0013 | 0.0016 | cGMP | - |
Rattus norvegicus | |
0.002 | 0.004 | cAMP | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
isozyme PDE11A | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | tissue-specific expression of splice-variants | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cAMP + H2O | - |
Rattus norvegicus | AMP | - |
? | |
cGMP + H2O | - |
Rattus norvegicus | GMP | - |
? |