Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | norepinephrine increases PLC beta1, beta3, gamma1, and delta1 isozyme gene expression | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | increases in PLC beta1, beta3, gamma1, and delta1 activities and gene expression in response to norepinephrine are prevented by prazosin, an alpha1-adrenoceptor antagonist; increases in PLC beta1, beta3, gamma1, and delta1 activities and gene expression in response to norepinephrine are prevented by prazosin, an alpha1-adrenoceptor antagonist; increases in PLC beta1, beta3, gamma1, and delta1 activities and gene expression in response to norepinephrine are prevented by prazosin, an alpha1-adrenoceptor antagonist; increases in PLC beta1, beta3, gamma1, and delta1 activities and gene expression in response to norepinephrine are prevented by prazosin, an alpha1-adrenoceptor antagonist | Rattus norvegicus | |
U-73122 | - |
Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
85000 | - |
Western blot analysis | Rattus norvegicus |
135000 | - |
Western blot analysis | Rattus norvegicus |
150000 | - |
Western blot analysis | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P10686 | - |
- |
Rattus norvegicus | P10687 | - |
- |
Rattus norvegicus | P10688 | - |
- |
Rattus norvegicus | Q99JE6 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cardiomyocyte | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O | - |
Rattus norvegicus | 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol | - |
? |
Synonyms | Comment | Organism |
---|---|---|
phospholipase C | - |
Rattus norvegicus |
PLC beta1 | - |
Rattus norvegicus |
PLC beta3 | - |
Rattus norvegicus |
PLC delta1 | - |
Rattus norvegicus |
PLC gamma1 | - |
Rattus norvegicus |