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Literature summary for 3.1.4.11 extracted from

  • Hao, J.J.; Liu, Y.; Kruhlak, M.; Debell, K.E.; Rellahan, B.L.; Shaw, S.
    Phospholipase C-mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane (2009), J. Cell Biol., 184, 451-462.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.4.11

Activating Compound

Activating Compound Comment Organism Structure
additional information activation of PLC is essential for SDF-1-induced ERM (ezrin/radixin/moesin) protein release from cortical membrane and dephosphorylation Homo sapiens

Protein Variants

Protein Variants Comment Organism
Y783F PLC construct Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information SFD-1-mediated inactivation of ERM (ezrin/radixin/moesin) proteins is blocked by phospholipase C inhibitors Homo sapiens
U-73122
-
 Homo sapiens
U-73343
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
confirmed by Coomassie blue staining after SDS-PAGE Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
JURKAT cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
PLCgamma1
-
 Homo sapiens