Literature summary for 3.1.4.11 extracted from

Makranz, C.; Cohen, G.; Baron, A.; Levidor, L.; Kodama, T.; Reichert, F.; Rotshenker, S.
Phosphatidylinositol 3-kinase, phosphoinositide-specific phospholipase-Cgamma and protein kinase-C signal myelin phagocytosis mediated by complement receptor-3 alone and combined with scavenger receptor-AI/II in macrophages (2004), Neurobiol. Dis., 15, 279-286.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Mus musculus	signaling of myelin phagocytosis mediated by complement-receptor-3 alone and by complement-receptor-3 combined with scavenger-receptor-AI/II involves phosphatidylinositol 3-kinase, phosphoinositide-specific phospholipase-Cgamma and protein kinase-C, the cascade phosphatidylinositol 3-kinase -> phosphoinositide-specific phospholipase-Cgamma -> protein kinase-C, and wide range modulation by protein kinase-C	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	signaling of myelin phagocytosis mediated by complement-receptor-3 alone and by complement-receptor-3 combined with scavenger-receptor-AI/II involves phosphatidylinositol 3-kinase, phosphoinositide-specific phospholipase-Cgamma and protein kinase-C, the cascade phosphatidylinositol 3-kinase -> phosphoinositide-specific phospholipase-Cgamma -> protein kinase-C, and wide range modulation by protein kinase-C	Mus musculus	?	-	?

Synonyms

Synonyms	Comment	Organism
phosphoinositide-specific phospholipase-Cgamma	-	Mus musculus
PLCgamma	-	Mus musculus

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Release 2023.1 (January 2023)