Literature summary for 3.1.4.11 extracted from

vom Dorp, F.; Sari, A.Y.; Sanders, H.; Keiper, M.; Oude Weernink, P.A.; Jakobs, K.H.; Schmidt, M.
Inhibition of phospholipase C-epsilon by Gi-coupled receptors (2004), Cell. Signal., 16, 921-928.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	Gi-coupled receptors can inhibit PLC-epsilon, most likely by suppressing formation of cyclic AMP required for Epac-mediated Rap2B activation	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HEK-293 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	Gi-coupled receptors can inhibit PLC-epsilon, most likely by suppressing formation of cyclic AMP required for Epac-mediated Rap2B activation	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
phospholipase C-epsilon	-	Homo sapiens
PLC-epsilon	-	Homo sapiens

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Release 2023.1 (January 2023)